Endocrine Abstracts

Introduction: Giant prolactinomas are rare tumors accounting for 2–16% of all prolactinomas. They may be aggressive and invasive. Rarely, they might not have a suprasellar component and grow downward. Such extension can make it difficult to distinguish pituitary adenoma from other skull base tumors. We present a case that was considered to be chordoma based on clinical and radiological imaging features, but was diagnosed as prolactinoma by pituitary biopsy.<p class="a...

Introduction: Coronavirus disease-19 (COVID-19) pandemic renders high morbidity and mortality. Glucocorticoid excess is characterized by increased susceptibility to infections due to impairment of the innate and adaptive immune system. Manifestations of Cushing disease (CD) including diabetes mellitus (DM), hypertension, and obesity are risk factors for severe COVID-19 disease. We present three CD patients with different clinical courses of COVID-19. The patients’ general...

Over the past decade there has been increased recognition of the dangers associated with inpatient management of diabetes insipidus (DI) and omission of desmopressin. An NHS England patient safety alert was issued in 2016 highlighting this risk.Method: Using electronic prescribing records we reviewed all desmopressin prescriptions and omissions over a 12 month period in a large teaching hospital.Results: Ninety-seven inpatients wer...

Over the past decade there has been increased recognition of the dangers associated with inpatient management of diabetes insipidus (DI) and omission of desmopressin. An NHS England patient safety alert was issued in 2016 highlighting this risk.Method: Using electronic prescribing records we reviewed all desmopressin prescriptions and omissions over a 12 month period in a large teaching hospital.Results: Ninety-seven inpatients wer...

Introduction: Insulinoma is a rare neuroendocrine tumor that is difficult to diagnose due to its obscure location. Conventional radiographic methods have low sensitivity and are inadequate to detect insulinoma. Selective arterial calcium stimulation test (SACST) is 95–100% sensitive in the diagnosis of insulinomas. Here, we presented two cases of insulinoma that could not be located by radiographic methods and evaluated them with SACST.Case 1: A 48-...

Background: Prolactinoma is the most common functioning pituitary adenoma. Subclinical atherosclerosis and cardiovascular risk in patients with prolactinoma were reported but have not been clarified yet.Aim: Our study aims to compare prolactinoma patients with a control group in terms of lipid profile, body fat distribution, and subclinical atherosclerosis markers.Methods: This single-center, prospective study included 32 patients ...

Background: Paragangliomas (PGLs) and pheochromocytomas (PCCs) arise from chromaffin cells. We evaluated the inflammatory markers. The pan-immune-inflammation value (PIV) has recently been used as a new marker. Therefore, we evaluated the PIV association in patients with PGLs/PCCs.Methods: In the study, the data of 82 patients with PGLs/PCCs who applied between 2005 and 2020 were collected retrospectively from the records. NLR (neutrophil/lymphocyte rati...

Thyroid cancer is the most common malignancy of the endocrine system. Papillary thyroid cancer is the most common thyroid malignancy worldwide and has a good prognosis. The prevalence of follicular thyroid cancer in endemic iodine deficiency regions is higher than in regions without iodine deficiency. However, it has been observed that the incidence of follicular thyroid cancer decreases and the incidence of papillary thyroid cancer increases after iodine prophylaxis. The Our ...

Aim: It has been reported that thyrotrophin receptor antibody (TRAb) is associated with frequency and aggressiveness of thyroid cancer in patients with Graves disease (GD). However, there is not any data regarding the effects of TRAb on cytology and histopathology results of patients with nodular GD. Thus, the aim of the present study is to evaluate the effects of TRAb on cytology and histopathology results in patients with nodular or multinodular thyroid disease on the basis ...

Purpose: Adrenal incidentalomas (AIs) are adrenal masses, which are found on imaging studies not performed related to an adrenal problem. Hepatic incidental masses and renal incidental masses are usually seen in abdominal imaging methods. We aim to investigate the frequency and the kind of hepatic and renal incidental masses in patients with AIs.Methods: Retrospective evaluation of 381 (245 female and 136 male) AI patients and 285 (168 female and 117 mal...